diff --git a/cmake/DetectOpenCV.cmake b/cmake/DetectOpenCV.cmake
index 196a551..a10a149 100644
--- a/cmake/DetectOpenCV.cmake
+++ b/cmake/DetectOpenCV.cmake
@@ -19,8 +19,10 @@ find_package(OpenCV REQUIRED)
 message(STATUS "Found OpenCV: ${OpenCV_VERSION}")
 if(OpenCV_VERSION VERSION_LESS 3.0)
   add_definitions(-DUSE_OPENCV2)
-else()
+elseif(OpenCV_VERSION VERSION_LESS 4.0)
   add_definitions(-DUSE_OPENCV3)
+else()
+  add_definitions(-DUSE_OPENCV4)
 endif()
 
 if(MSVC OR MSYS OR MINGW)
diff --git a/samples/api/CMakeLists.txt b/samples/api/CMakeLists.txt
index 8100370..4c27086 100644
--- a/samples/api/CMakeLists.txt
+++ b/samples/api/CMakeLists.txt
@@ -30,8 +30,12 @@ make_executable(camera_a
 
 ## get_depth_with_region
 
+if(OpenCV_VERSION VERSION_LESS 4.0)
+
 make_executable(get_depth_with_region
   SRCS get_depth_with_region.cc
   LINK_LIBS mynteye ${OpenCV_LIBS}
   DLL_SEARCH_PATHS ${PRO_DIR}/_install/bin ${OpenCV_LIB_SEARCH_PATH}
 )
+
+endif()